This study was performed to determine the ideal mixing ratio of toothash and plaster of Paris. The histopathologic and histomorphometric study of bone response of five implant materials, toothash(Group A), tooth and plaster mixture, mixing ratio
due to
weight 2 : 1(Group B), 3 : 1(Group C), 4 : 1(Group D), and plaster of Paris(Group E), were performed in rat calvarial defect. No sign of extensive inflammatory reaction was detected. Newly-formed bony ingrowth occurred in all experimental groups
except
for group E at 12 weeks after operation. Bone was deposited directly on the surface of implant materials. The highest rate of direct bony union between implant material and newly-formed bone occurred with the group B, followed group C, D, and A.
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